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SUMMARY:Heavy-Ion Track Structure and Target Dose Deposition Simulations U
 sing Geant4-DNA
DTSTART;VALUE=DATE-TIME:20261027T162500Z
DTEND;VALUE=DATE-TIME:20261027T163000Z
DTSTAMP;VALUE=DATE-TIME:20261027T165155Z
UID:indico-contribution-6506@cern.ch
DESCRIPTION:Speakers: Matvey Vologzhin (Tomsk State University)\nHeavy ion
 s within the Galactic Cosmic Ray (GCR) spectrum present a primary challeng
 e for radiation risk assessment in deep-space exploration and astroparticl
 e physics. Accurate description of their biological effectiveness requires
  multi-scale Monte Carlo simulations that account for both nanoscale stoch
 astic ionization patterns and macroscopic energy deposition in target volu
 mes.\n\nIn this work\, we investigate the performance and applicability of
  the Geant4 and Geant4-DNA toolkits for modeling the track structure of ch
 arged particles\, ranging from light ions to intermediate-mass nuclei. Ben
 chmark calculations were conducted for critical physical and nanodosimetri
 c endpoints\, specifically Radial Dose Distributions (RDD) and Ionisation 
 Cluster Size Distributions (ICSD)\, across different particle energies and
  physics constructors. \n\nIn addition\, we examine a multi-scale simulati
 on framework to evaluate absorbed dose distributions in target geometries\
 , accounting for particle transport through surrounding structural materia
 ls. The impact of the secondary radiation field generated along the beam p
 ath on the resulting spatial dose profile is assessed. This study demonstr
 ates the connection between validated nanoscale track-structure metrics an
 d macroscopic dose calculations\, providing a robust methodological founda
 tion for radiation transport modeling in space radiobiology.\n\nhttps://in
 dico.particle.mephi.ru/event/626/contributions/6506/
LOCATION:Sevastopol hotel Conference Hall 1
URL:https://indico.particle.mephi.ru/event/626/contributions/6506/
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